TAGMe DNA Methylation Detection yePan-cancer
Product features
Minimally invasive treatment:Bvisa kanenge 3mL Peripheral venous ropa kana mamwe akakodzera ekiriniki emuenzaniso mhando
Kururama:Tora data hombe uye AI algorithm, bvunzo chaiyo≥95%
Zvakasiyana-siyana:Kuonekwa kumwe chete kunogona kuvhara 25 high-icidence malignant tumors.
Danho rekutanga:Kupindira kubva mukutarisisa kwekutanga kwegomarara, mukati mese maitiro ekuongororwa uye kurapwa.
Zvakanakira:Tora zviyero zvegoridhe zvekuonekwa kwemethylation - pyrophosphate sequencing tekinoroji, inogona kupedza bvunzo mukati memaawa mana.
Chiremera:Iine makumi mashanu neina epasi rese uye epamba patents, mhedzisiro yekutsvagisa yakakodzera yakaburitswa muCancer Research, Genome Research uye mamwe epasi rose ane mukurumbira magazini.
Detection Principle
Iyo yese-kenza yekuona ndeye plasma ctDNA methylation test zvigadzirwa zvinogadzirwa neTAGMe, izvo zvinoda inokwana 3ml yeropa rese kuti inyatso kutora uye kuona iyo methylation mamiriro eiyo ctDNA's yakakosha nzvimbo yekumisikidza, kuitira kuti uwane yekutanga kuongororwa uye kunyatso tarisisa. yebundu.
Performance
Mukuongororwa kweanopfuura mazana matatu emakiriniki samples, iyo methylation level yeTAGMe mumabundu matissue yaive yakanyanya kukwirira kupfuura yeyakajairika tishu.Naizvozvo, TAGMe inogona kuiswa senge pan-cancer marker pakuona kweakasiyana magomarara.
Majini ane hukama neHistone ane hypermethylated mukenza yemapapu uye hypermethylated HIST1H4F inogona kushanda sepan-cancer biomarker.
--- Cancer Research, IF: 12.7
Semucherechedzo wegomarara repan-cancer, TAGMe ine hunyanzvi hwepamusoro uye kunzwisiswa mukusimbisa sampuli yekiriniki, iyo ine kukosha kwereferensi yekuongororwa kwekiriniki yemamota.
TAGMe inonzwisa tsitsi mune dzakasiyana tumor samples kana iyo chaiyo yakakura kupfuura 95%,
Maitiro ekushandisa
Nhoroondo yemhuri yegomarara:Varwere vegomarara mune vepedyo kana chibvumirano hama.
Utachiona hwehutachiona uye zvirwere zvisingaperi:Zvakadai seHPV, HBV uye humwe hutachiona hwehutachiona, intestinal polyps, chisingaperi atrophic gastritis uye chiropa cirrhosis, nezvimwe.
Yakaratidzwa kune carcinogenic nharaunda kwenguva yakareba:Yakaratidzirwa kune nharaunda yemwaranzi kana makemikari ane njodzi kwenguva yakareba.
Zvinofungidzirwa kuti bundu chiratidzo:zvakadai sekubuda ropa kusingaenzaniswi kwechikadzi, hematochezia, weti, mapundu emapapu, fivha isingatsananguriki kana kupera simba, nezvimwe.
Hunhu husina kunaka hwekugara kwenguva refu: Kusvuta kwenguva refu kana kusvuta, kunwa zvakanyanya, kudya kunopisa kana kunwa kunopisa, kunwa munyu wakawanda, kunyura, kuvhuvhuta, kuputa uye zvakakangwa zvekudya, nezvimwe.
Chenjerera kune wega hutano mamiriro:kunyanya kuboka rine makore anopfuura makumi mana