TAGMe DNA Methylation Detection Kits (qPCR) yeEndometrial Cancer
PRODUCT FEATURES
Precision
Yakasimbiswa pamusoro pe800 yemakiriniki masampuli mune kaviri-mapofu akawanda-epakati zvidzidzo, chigadzirwa chine chaiyo ye82.81% uye kunzwa kwe80.65%.
Convenient
Iyo yekutanga Me-qPCR methylation yekuona tekinoroji inogona kupedzwa mudanho rimwe mukati meawa matatu pasina bisulfite shanduko.
Kurumidza
Detectable at the precancerous stage.
Automation
Inoshanda necervical brush uye Pap smear samples.
ZVIRI KUSHANDISA
Iyi kit inoshandiswa in vitro qualitative yekuona hypermethylation yejini PCDHGB7 incervical specimens.Mhedzisiro yakanaka inoratidza kuwedzera kwengozi ye endometrial precancerous maronda uye kenza, izvo zvinoda kuwedzera histopathological kuongororwa kweendometrium.Kusiyana neizvi, mhinduro dzisina kunaka dzebvunzo dzinoratidza kuti njodzi ye endometrial precancerous maronda uye kenza yakaderera, asi njodzi haigone kubviswa zvachose.Kuongororwa kwekupedzisira kunofanirwa kuve kwakavakirwa pane histopathological kuongororwa mhedzisiro ye endometrium.PCDHGB7 inhengo yemhuri yeprotocadherin γ gene cluster.Protocadherin yakawanikwa inodzora zvipenyu zvakaita sekuwedzera kwesero, kutenderera kwesero, apoptosis, kupinda, kutama uye autophagy yemasero ebundu kuburikidza nenzira dzakasiyana-siyana dzekusaina, uye kunyarara kwemajini kunokonzerwa ne hypermethylation yedunhu rinosimudzira zvine hukama zvakanyanya nekuitika uye kusimudzira. kenza dzakawanda.Zvinonzi hypermethylation yePCDHGB7 inosanganiswa nemhando dzakasiyana-siyana dzemamota, akadai seasiri Hodgkin lymphoma, kenza yemazamu, kenza yechibereko, endometrial cancer uye dundira.
ZVINHU ZVINOTAURWA
Iyi kit ine nucleic acid yekubvisa reagent uye PCR yekuona reagent.Nucleic acid inobviswa nemagnetic-bead-based method.Iyi kit yakavakirwa pamusimboti wefluorescence quantitative PCR nzira, uchishandisa methylation-specific real-time PCR reaction yekuongorora template DNA, uye panguva imwe chete kuona CpG nzvimbo dzePCDHGB7 gene uye yemhando yekudzora marker yemukati referensi gene zvidimbu G1 uye G2.Iyo methylation level yePCDHGB7 mumuenzaniso, kana iyo Me value, inoverengerwa maererano nePCDHGB7 gene methylated DNA amplification Ct kukosha uye Ct kukosha kwereferensi.Iyo PCDHGB7 gene hypermethylation yakanaka kana isina kunaka chimiro inotarwa maererano neMe value.
Maitiro ekushandisa
Kuongororwa kwekutanga
Vanhu vane hutano
Cancer Risk Assessment
Mapoka ane njodzi huru (vanhu vane kubuda ropa kusiri kwechikadzi mushure mekuenda kumwedzi, kupera kwe endometrial, nezvimwewo)
Recurrence Monitoring
Prognostic population
Clinical kukosha
Kuongororwa kwekutanga kwehuwandu hwevanhu vane hutano:Endometrial cancer uye precancerous maronda anogona kunyatsoongororwa kunze;
Kuongororwa kwenjodzi kune vanhu vane njodzi huru:Kuongororwa kwengozi kunogona kuitwa kune vanhu vane ropa risina kujairika uye endometrial thickening mushure mekuenda kumwedzi kuti vabatsire mukuongororwa kwekliniki;
Prognostic kudzokororwa kwehuwandu hwevanhu:Postoperative recurrence monitoring inogona kuitwa kudzivirira kunonoka kurapwa kunokonzerwa nekudzokorora.
Sample collection
Sampling nzira: Isa cervical sampler inoraswa pacervical os, zvinyoro nyoro puruzira cervical brashi uye tenderedza 4-5times wachi, bvisa zvishoma nezvishoma cervical brashi, woiisa mucell preservation solution, woinyora pakuongorora kunotevera.
Kuchengetedza sampuli:Masamples anogona kuchengetwa pakamuri tembiricha anosvika mazuva gumi nemana, pa2-8 ℃ kweanosvika mwedzi miviri, uye pa -20±5℃ kusvika kumwedzi makumi maviri nemana.
Maitiro ekuona: Maawa matatu (Pasina manyorero maitiro)
TAGMe DNA Methylation Detection Kits (qPCR) yeEndometrial Cancer
| Clinical application | Kliniki yekubatsira kuongororwa kwe endometrial carcinoma |
| Detection gene | PCDHGB7 |
| Muenzaniso mhando | Mienzaniso yekervical yevakadzi |
| Test method | Fluorescence quantitative PCR tekinoroji |
| Mienzaniso inoshanda | ABI7500 |
| Packing specification | 48 bvunzo/kiti |
| Storage Conditions | Kit A inofanira kuchengetwa pa2-30 ℃ Kit B inofanira kuchengetwa pa -20±5℃ Inoshanda kusvika kumwedzi gumi nemiviri. |
Nezvedu
Epiprobe ine yakakura yekuvaka zvivakwa: GMP yekugadzira nzvimbo inovhara nzvimbo ye 2200 square metres, uye inochengetedza ISO13485 quality management system, iyo inosangana nezvinodiwa zvekugadzirwa kwemarudzi ese emhando yemagetsi ekuongorora reagent zvigadzirwa;rabhoritari yezvokurapa inovhara nzvimbo inosvika 5400 square metres uye inokwanisa kuita bhizinesi rekuona gomarara semethylation yakasimbiswa yechitatu-bato rabhoritari yekurapa.Kunze kwezvo, isu tine zvigadzirwa zvitatu zvakawana CE certification, inovhara gomarara rechibereko, endometrial cancer uye urothelial cancer inoenderana nekuonekwa.
Epiprobe's cancer mamorekuru ekuona tekinoroji inogona kushandiswa kwekutanga kenza kuongororwa, yekubatsira kuongororwa, preoperative uye postoperative yekuongorora, recrudescence monitoring, iyo inomhanya kuburikidza nehurongwa hwese hwekuongororwa kwegomarara uye kurapwa, ichipa mhinduro dziri nani kune vanachiremba nevarwere.
