Chii chinonzi TAGMe
Pasi rose zvakasarudzika: Tumor Aligned General Methylated Epiprobe (TAGMe)
Mukuongororwa kweanopfuura mazana matatu emakiriniki samples, iyo methylation level yeTAGMe mumabundu matissue yaive yakanyanya kukwirira kupfuura yeyakajairika tishu.Naizvozvo, TAGMe inogona kuiswa senge pan-cancer marker pakuona kweakasiyana magomarara.
Majini ane hukama neHistone ane hypermethylated mukenza yemapapu uye hypermethylated HIST1H4F inogona kushanda sepan-cancer biomarker.
————Cancer Research,IF:12.7
Detection performance
Semucherechedzo wegomarara repan-cancer, TAGMe ine hunyanzvi hwepamusoro uye kunzwisiswa mukusimbisa sampuli yekiriniki, iyo ine kukosha kwereferensi yekuongororwa kwekiriniki yemamota.
TAGMe inonzwisa tsitsi mune dzakasiyana tumor samples kana iyo chaiyo yakakura kupfuura 95%,